Associate Scientist Analytical Development

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. You will work with outstanding people who together pioneer the research, development and commercialization of bi-specific TCR therapies. We aim to create an environment where individual contributions and initiatives can be maximized, while fostering a culture of collaboration, based on respect and integrity. We want each individual employee to own their career, as part of high-performing teams, and in the context of on-the-job and formal continuous development and training, as well as constructive feedback. We always strive to identify ways to improve what we do and how we do it, by asking questions, voicing opinions, exploring various approaches and staying connected with healthcare professionals, patients, academia and other key partners.
To support analytical scientists in the development of cell based potency and plate based immunoassays that are used for the analysis of ImmTAX and other TCR based molecules to support stability, lot release and characterisation studies as part of product development. To role will provide scientific and technical support to the team of bioassay scientists. The Associate Scientist will conduct experimental investigation, with supervision and guidance from colleagues and managers, enabling the advancement of the company pipeline, process, or technology capabilities.
KEY RESPONSIBILITIES
* Support development and qualification of bioassay (cell based potency and immuno-analytical) methods to support drug substance (DS) and drug product (DP) release and stability testing for the Immunocore therapeutic drug portfolio.
* Support investigative and characterisation studies using bioassay methods.
* Run pre-established experimental investigations, with guidance from line managers, a mentor or colleagues.
* Analyse data obtained with minimal supervision
* Contribute to authoring technical documents including development reports, analytical test methods, and method qualification reports.
* Maintain cells required in cellular potency assays to the appropriate standards.
* Support the stock control, purchasing and distributing lab reagents and consumables
* Priorities: working to agreed experimental priorities and deadlines; raising issues or concerns with managers or colleagues so that these can be addressed.
* Technical knowledge: actively developing own knowledge, drawing on the experience of others and self-learning.
* Laboratory records: Ensuring that all records and data are up to date, on time and recorded to the correct standard, checking with a mentor or colleagues if unsure.
* Laboratory equipment: attending training on the use of technical instruments, using equipment appropriately, correctly and tidily.
* Health & Safety: compliance with all H&S requirements, attending appropriate training programmes.
Other
* Commitment to growing and learning laboratory skills and scientific theories
Experience & knowledge
Essential
* A background in biochemical or related laboratory work, with one or more years' experience gained in industry.
* A strong background in biochemical and immunological techniques
* Competence in word processing, spreadsheets, presentation and relevant scientific software
* Strong communication skills (verbal and written).
* Recorded results and information in a concise, accurate and timely way
* Learned about new practices through observation, self-learning and an enquiring mind
* Worked and contributed actively in a diverse team environment
Desirable
* Prior knowledge of developing cell based potency or immunoassays (eg ELISA)
* Experience of lab organisation/maintenance
* Proactive in ensuring high quality of their work and seeking additional responsibilities to help meeting the goals of the team
Education & qualifications
* BSc. in Biochemistry, Biological Sciences, Immunology or related discipline