Senior Process Scientist

THE COMPANY

Glen Clova Scientific Ltd (GCS) is developing a new generation of Active Biologics to treat inflammatory conditions. We are an ambitious spinout from the University of Dundee aiming to address the global need to make effective treatments available for millions of patients. Our novel Virus-Like-Particle technology is poised to address inherent limitations of the current blockbuster class of Biologic drugs. Our vision is to make high end biotech pharmaceuticals much more accessible to patients than current blockbusters. If you aspire not only to be at the core of biotech innovation but also to tackle the global problem of high-cost medicine, this is a rare opportunity to join a highly dynamic team.

LOCATION

Dundee is an up- and coming Biotech centre in a fantastic setting: Multiple beaches are within easy reach; housing is highly affordable even in catchments of nationally top-performing independent and state schools; there is a multitude of child-care providers. Dundee is a large university centre with a multi-cultural scene and vibrant night life, an award-winning theatre playhouse, a variety of museums. Transport and connections are excellent: the stunning Scottish Highlands can be reached in 45 minutes; the cultural buzz, and global airport connectivity of Edinburgh is 1h by train in addition to direct rail links to Glasgow (90 minutes) and Aberdeen (60 minutes).

JOB DESCRIPTION

You will work in a team of fellow scientists and technicians, directly reporting to the CSO. You will be responsible for developing lab scale Downstream Processes (DSP) for our pipeline of Active Biologic Drugs, using technologies that can be scaled and transferred to industrial manufacturing units. You will employ a variety of chromatography techniques, using both FPLC (Akta) systems and manual and batch designed set-ups as appropriate. You will also include process components for endotoxin removal. You will supervise and coordinate the work of technicians assisting in this task. You will coordinate work schedule closely with scientists and technicians focussing on Upstream Process.

EXPERIENCE AND QUALIFICATIONS

You hold a PhD in a subject related to Downstream Process, and/or or several years relevant industrial experience. You have experience with pilot scale FLPC, and extensive experience in a variety of protein chromatography techniques.

KEY REQUIREMENTS

• Practical experience of recombinant protein expression in E.coli and, preferably, also other platforms (eg. Mammalian, insect cells).
• Documented experience in protein purification including IMAC, IEC, SEC, IEX, HIC, fusion protein cleavage technologies, use of AKTA system-based chromatography, as well as related analytical technologies.
• Ability to work independently, to read pertinent literature and understand emerging technology developments.
• Team player personality and excellent troubleshooting skills.
• Excellent record keeping, writing and presentation skills, including drafting of reports.
• Ability to work under pressure of milestone – driven timelines
• Willingness to work flexibly when required to deliver priority actions

ADDITIONAL BENEFITS

• Relocation allowance
• Transport / Parking: Free on-site parking (or free car park pass);
• Holiday: 24 days plus Scottish public holidays
• Maternity Leave: after 1 year of employment:
• Company options after a qualifying period of employment
• Company bonus scheme entitlement after completion of a qualifying probation period
• Pension scheme: Employer contributions into a personal private pension plan as % of income

Please note that only qualified candidates will be contacted for further consideration.

Job Type: Full-time

Benefits:

• Canteen
• Company pension
• Employee stock purchase plan
• Free parking
• On-site parking
• Relocation assistance

Schedule:

• Monday to Friday

Supplemental pay types:

• Bonus scheme

Ability to commute/relocate:

• Dundee: reliably commute or be willing to relocate with an employer-provided relocation package (required)

Education:

• PhD (required)

Experience:

• relevant industry: 2 years (required)

Work Location: In person

Application deadline: 19/04/2024
Reference ID: GCS I