Senior Research Associate

Job Title: Senior Research Associate- Synergy

Location: Cambridge, UK

Salary: £33,000 - 35,000 p/a

contract: 12 month FTC

A highly motivated Senior Research Associate (SRA) in protein biochemistry and molecular assays. The SRA will be responsible for the production of condensate-forming proteins and carry out compound screening using our proprietary microfluidic platform, activities that are critically important to the success of our drug-discovery program.

This role will require a good knowledge of problem-solving capability to successfully express and purify challenging protein systems from heterologous hosts. The candidate should demonstrate expertise and technical proficiency in molecular biology and protein chromatography methods. Comprehensive training will be provided for the operation of our specialized screening technologies.

Synergy, part of SRG, offer a range of scientific solutions to different Clients in the Life Sciences sector. We can offer a competitive salary, a range of excellent benefits and access to training & development opportunities within the role.

Responsibilities:

• Express and purify recombinant proteins, including cloning and construct generation.
• Problem solve and innovate to produce proteins in large scales from heterologous expression systems including insect and bacterial cells.
• Analyse data, troubleshoot technical difficulties, implement solutions, and present results regularly at team meetings.
• Maintain and implement laboratory practices to a high standard, including accurate record keeping using electronic laboratory notebook systems.
• Work effectively and collaboratively with cross-disciplinary teams to contribute to the vision, strategy, and tactics of the organization.

Requirements:

• BSc/MSc in Biochemistry, Biophysics, or a related field, or sufficient industry experience.
• Solid industry experience, working in protein biochemistry, molecular biology, or related disciplines (2-3 years).
• A demonstrated ability to design and execute recombinant protein expression and purification strategies using mammalian, insect, yeast, bacterial and cell free expression systems.
• Understanding of protein structure-function relationships and protein-ligand interactions.
• Experience in efficiently producing high-quality data from molecular assays and contributing to high-throughput screening projects would be an advantage.
• Proficient in producing high-quality data from routine molecular assays to set deadlines.
• Technical proficiency in molecular biology and protein purification methods, including Gibson cloning, diverse chromatography techniques and operating an AKTA protein purification platform.
• Ability to organise, analyse, and deliver information in a concise, accurate, and professional manner including the use of electronic laboratory notebooks; strong written and oral communication skills; excellent data management skills.

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.