Translational Scientist - Prof. Owen Sansom

Scotland Institute lab: Colorectal Cancer and Wnt Signalling  Contract Term: Fixed up to 1 year. About us The CRUK Scotland Institute (formerly Beatson Institute) is a cancer research institute, situated in Glasgow with approximately 250 researchers split across 30 research groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis. Its research ethos is about excellence, honesty, openness, accountability and integrity. Position outline A Senior/Principal scientific officer position is available for a translationally minded scientist to join the Colorectal Cancer and Wnt Signalling team to drive preclinical research. The project will require the delivery of biopharma-funded translational research and will focus upon development of novel therapeutic approaches relevant to colorectal cancer, related to the WNT and RAS signalling pathways. Both in vitro and in vivo will be undertaken in delivering this project, which will determine the therapeutic efficacy of WNT or RAS pathway targeting. Briefly, the project involves the transcriptional and functional characterisation of pharmacomimetic loss-of-function mutations in murine models of colorectal cancer. As an ideal candidate, you will be an experienced researcher having completed at least one position after completion of a relevant PhD. You must have expertise in working with murine cancer models, and have a strong background in molecular biology and cellular signalling. The ability to work as part of a team and to effectively plan and prioritize workflows to facilitate project delivery will be an advantage. For informal enquiries about the research, please email Dr. Andrew Campbell at a.campbell@crukscotlandinstitute.ac.uk Equality, Diversity and Inclusion Our overarching research ethos at the Institute is about excellence, honesty, openness, accountability and integrity. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters. The Institute is also committed to increasing the number of female scientists at the postdoc level and beyond and encourages female applicants to apply. We have recently introduced a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children amongst other family friendly policies Employee Benefits Competitive salary 40.5 days annual leave including bank holidays (pro-rata) Defined Contribution pension scheme Life Insurance scheme Employee Assistance Programme Season ticket loan Additional maternity pay at 6 month’s full pay (subject to service) Shared parental leave Cycle to work scheme that could save you 26-40% on a bike and accessories. Access to Employee benefit schemes with discounts on supermarkets, cinema, travel and much more. On-site secure parking All applications must be made via our website by clicking on the 'Apply' button above. Closing Date for applications: 09 June 2024