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Form of work
SalaryAn exciting opportunity to join a market leading Biotechnology business, working within their fully equipped research laboratories in Cambridge, alongside a group of Scientists who are considered world leaders in their field.
The business prides themselves on their open and collaborative way of working. They offer a comprehensive range of benefits including pension, private healthcare, generous holiday allowance, flexitime, bonus and more!
The Role
This is a fixed term, full time lab-based position within the Protein Sciences team. The role has a focus on generating high quality proteins to support drug discover programmes by enabling NMR, X-ray crystallography and biochemical assays.
Main responsibilities:
- Production and QC of high-quality proteins suitable to enable drug discovery programmes.
- Presentation of work at project meetings and to external partners
- Liaising with Protein Science Team Leader and Project Leaders to ensure the needs of projects are met.
- Contributing to the safe and efficient running of the laboratory
- Knowledge and Experience
Essential criteria - Experience working with multiple expression systems e.g. Bacterial / Insect (BEVS) / Mammalian
- Hands-on experience with protein purification
- Experience using AKTA purification systems e.g. AKTA Pure
- Competent using IMAC/IEC/SEC techniques.
Desirable criteria- Previous experience working within an industrial lab-setting.
- Familiarity with intact mass spectrometry analysis of proteins
- Knowledge of using TSA/DSF for protein QC
- Experience generating isotopically labelled proteins.
- Familiarity with molecular biology software e.g. VectorNTI or CLC Main Workbench
- Experience assessing structure of protein using PyMol
Skills and Personal Competencies- Effectively communicate results to key stakeholders
- A commitment to excellent record keeping, i.e. recording experiments in electronic lab books and various internal databases.
- Have a good eye for detail; able to spot inconsistencies and errors in the work you generate.
- Able to work as part of a team or individually
- Qualifications
PhD graduate or BSc graduate with industry experience
If you are passionate about drug discovery and would love to join a team where scientific excellence and enthusiasm combine in a friendly and flexible environment, then contact me today!
