Job description
Full time, fixed-term appointment to 31st December 2027 Based in Liverpool with international travel LSTM's Vector Biology Department seeks a highly motivated Postdoctoral Research Associate (Chemist or Biochemist) to join our dynamic team and contribute to a ground-breaking research program focused on insecticide resistance in malaria vectors. This stimulating four-year project offers a unique opportunity to make a significant impact on the fields of chemical biology and resistance research to unravel the mechanisms of insecticide resistance in mosquitoes and contribute to the development of an innovative Insecticide Resistance Prediction Platform (IRPP). This project, funded by the Bill & Melinda Gates Foundation, aims to deepen our understanding of insecticide resistance to novel vector control products developed to control malaria-transmitting mosquitoes. Reporting directly to Dr. Hanafy M. Ismail, the Project Principal Investigator, your primary responsibility will involve leading the design and creation of a specialized chemical-proteomic discovery pipeline. Key responsibilities are (but not limited to): Work in partnership with the Chemist - PDRA and Project PI on the design and synthesis of click-chemistry insecticide probes and protein degraders. Utilize quantitative proteomics, protein degraders, and molecular biology assays to unravel the non-covalent interactions between emerging insecticides and their protein targets in Anopheles mosquitoes. Supervise essential laboratory operations and collaborate closely with a multidisciplinary team of chemists, bioinformaticians, molecular biologists, and entomologists to achieve the project goals and objectives. Disseminate research findings through publications and presentations, enhancing global understanding of vector biology and disease control. Why Join Us? Engage in cutting-edge chemical biology research with a tangible impact on global health. Collaborate with world-renowned experts in malaria control research in a dynamic research environment. Access state-of-the-art analytical chemistry facilities at LSTM and the Material Innovation Factory at the University of Liverpool. Grow professionally and contribute to research that makes a difference. The ideal candidate will demonstrate: PhD in Chemical Biology, Biochemistry, or a related field. Demonstrated expertise in quantitative proteomics research pipelines. Strong molecular biology skills. Excellent communication and collaboration skills. Passion for research and a commitment to global health. (Please refer to the job description and person specification for the full list of essential and desirable criteria) Join LSTM and make a real difference in the fight against malaria! Additional benefits of joining LSTM: 30 days annual leave, plus bank holidays, plus Christmas closure days Generous occupational pension schemes Government backed “cycle to work” scheme. Affiliated, discounted staff membership to the University of Liverpool Sports Centre Application Process: To apply for the position please follow the apply link and upload your CV and covering letter. Due to the volume of applications, we receive, we may close our vacancies early. It is therefore advisable to apply as early as possible if you would like to be considered for a role. Inclusion is central to our values at LSTM. Look at some of the great work we have achieved in our annual report: www.lstmed.ac.uk/about/annual-reports-and-financial-statements LSTM actively promotes Equal Opportunities and Safeguarding Policies Please note the Recruitment Office will be closed from 20th December, and re-opens on 2nd January 2024.