Address
Form of workCombinatorial Biosynthetic Pathway Engineering (an EPSRC-funded project)
Project summary: The development of efficient microorganism-driven processes that generate bioactive natural products is of immense biotechnological, biomedical, environmental, and economic importance.
This project will transform Biosynthetic Pathway Engineering into a more predictable and efficient process through integration of combinatorial assembly and automated pathway variant analysis with holistic modelling procedures that incorporate genetic-, metabolic- and resource-related factors. This will be underpinned by novel technological approaches married to advanced computational strategies.
This project will generate important new fundamental understanding of how complex pathway control is achieved in living cells as well as procedures of value to the commercial sector.
If you are interested in participating in a cutting-edge research programme that involves state-of-the-art experimental and computational tools to answer fundamental questions about cellular control of genetic and metabolic processes, do apply.
Research groups: This is a collaborative interdisciplinary project involving the McCarthy and Alberti groups in the School of Life Sciences, plus the Darlington group in the School of Engineering, at Warwick University.
Researchers on this project will have access to outstanding facilities for molecular biology and biochemistry, as well as state-of-the-art analytic instrumentation and robotic platforms (https://warwick.ac.uk/fac/sci/lifesci/tic).
