Address
Form of workOur client has more than 11,000 people worldwide with operations in the U.S., Asia, Europe & Japan and is one of the world's leading research-based pharmaceutical companies.
The teams focus on the identification of drug targets for neurological diseases (especially Alzheimer’s disease and Parkinson’s disease). Drug targets are investigated with a view to discovering compounds and other agents that could modulate the target to give benefit in disease.
Research Biologist/Senior Research Biologist Role:
You will be focusing on the development and utilisation of complex cell-based and biochemical assays for drug identification and pharmacological profiling.
Specific techniques may include:
- Cell culture (cell lines and more advanced systems),
- Working with antibodies (immunostaining, immunoblotting etc.) enzyme assays and screening,
- Working with recombinant proteins,
- Molecular biology techniques (generating/handling constructs, transfections etc.)
- Various types of laboratory instrumentation (plate readers, liquid handling, imaging etc.).
Your Background:
- MSc/PhD in a relevant biological science with basic and some advanced laboratory skills in biochemistry, cell biology, molecular biology, pharmacology, neuroscience or a related discipline.
- Experience in R&D methods and processes. Experience in industry would be an advantage but is not essential.
- Experience in or knowledge of the pharmaceutical drug discovery process is highly desirable.
- Knowledge of assay development for screening using small compound libraries.
- Ability to work in new areas (reagent development, assay development, cell-system set-up and validation) is essential.
- Able to work independently, albeit with discussion of strategy and data with supervisor.
- Ability to design, schedule, execute and interpret experiments using complex biological systems eg native tissue, cell culture, western blotting assays, screening technologies.
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 56459 in all correspondence.
Please note:
This role is subject to satisfactory completion of a basic Disclosures and Barring Service (DBS) check.
