Address
Form of work
SalaryCRUK Research Fellow in Cancer Immunoprevention
Cancer Sciences
Location: Southampton General Hospital
Salary: £41,732 to £42,978 per annum
Full Time, Fixed Term
Closing Date: Friday 22 March 2024
Interview Date: To be confirmed
Reference: 2628624CM
We are seeking to recruit a highly motivated and capable postdoctoral researcher to join the Cancer Immunoprevention laboratory, led by Dr Matthew Rose-Zerilli at the University of Southampton. The successful candidate will join the multidisciplinary Innovation for Translation Research Group in the Faculty of Medicine, composed of both basic scientists and clinicians, providing a rich environment for exciting professional and personal development.
Supported by the research charity Cancer Research UK and our local Centre for Cancer Immunology Talent Fund, this translational research project will integrate single-cell transcriptomic approaches with cellular biology, immunology and 3D tissue mucosoid modelling to understand how the activity of human eosinophils can be harnessed for Cancer Immunoprevention.
The post holder will work on a collaborative project (including collaborators from Clinical and Experimental Sciences, UHS and Oxford University) seeking to understand the molecular mechanisms underpinning the negative association between eosinophilia and malignant transformation in the distal oesophagus. The post will be funded until 30/04/2026 in the first instance.
Candidates should have a PhD in a relevant area and a BSc/MSc in a related life science subject (e.g. cell biology/ immunology). A background or strong interest in innate immunity and tumorigenesis would be beneficial.
The candidate will have robust skills in molecular biology techniques as well as experience in innate immune cell culture, primary tissue explants, flow cytometry and 3D cell culture/ organoid techniques. Experience with confocal microscopy and using the programming language R is desirable. Training will be provided in droplet-based single-cell transcriptomics. The candidate must have excellent organisational, communication and problem-solving skills. Evidence of a successful track record in research and the ability to work independently as well as part of a team is required.
Please note that applications from agencies will not be accepted unless indicated on the job application.
As a university, we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. With a generous holiday allowance as well as additional university closure days, we are committed to supporting our staff and students and open to a flexible working approach.
Apply by midnight on the closing date.
Other organisations may call this role Senior Research Assistant, Research Associate, Researcher, Postdoctoral Researcher, Healthcare Researcher, Cancer Care Researcher, Postdoc Researcher, or Multidisciplinary Research Fellow.
Job Types: Full-time, Temporary contract
Salary: £41,732.00-£42,978.00 per year
Work Location: In person
Reference ID: 2628624CM
