Research Assistant

Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalised recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.

Our client is a London, UK-based private biopharmaceutical company committed to delivering truly innovative, life-changing therapies for patients. Our vision is to become a leading global biopharmaceutical company, offering transformational and valued therapies for autoimmune and inflammatory diseases, and preventing rejection in organ transplantation, based on modular engineered Tregs.

They are seeking a Research Associate to join a dynamic R&D group performing various immune-based assays. This role offers an excellent opportunity for a talented and motivated scientist to contribute to a growing pipeline of assets in an exciting and highly dynamic environment focused on developing cutting-edge cellular therapies.

Key Responsibilities:

• Conduct molecular and cell-based assays to enhance the understanding of CAR-Tregs and their impact in preclinical in vitro and in vivo models.
• Assist in the development of novel assays and methods to investigate CAR-Treg cell function.
• Aid in the development and testing of innovative and relevant immune regulatory assays/models.
• Collaborate with and support scientists within the translational medicine group.
• Provide support in day-to-day laboratory operations to ensure the smooth running of lab teams.
• Author experiment write-ups and reports.
• Create and maintain compliant process documentation.
• Work with external service providers as required.
• Supervise staff as necessary.
• Compile batch documentation and ensure accuracy.
• Participate in the manufacture of research-grade viral vector products.

Reporting Relationships:

• Reports to the Group Leader on Research & Development.
• Works closely with other members of the Scientific Research & Development team, CMC, and Process Development team.

Essential Qualifications & Experience:

• BSc/MSc in Biology/Immunology or related discipline.
• Familiarity with a range of immunological cell-based techniques and tests.
• Experience with mammalian cell culture, ideally human immune cell culture.
• Excellent organizational skills with the ability to present results clearly and logically, working cooperatively as part of a team and independently.
• Ability to efficiently identify and implement solutions to improve processes.
• Good attention to detail and record keeping.
• Excellent time and project management skills with the ability to prioritize activities.
• Proven commitment to high-quality work and maintenance of high standards.
• Solid understanding of cell biology and immunology.
• Strong verbal and written communication skills.
• Contribution to a culture that embraces scientific excellence, integrity, urgency, patient centricity, and continuous improvement.

Desired Skills and Experience:

• Familiarity with a range of immunological cell-based techniques and tests, e.g., Flow Cytometry, ELISA.
• Experience with mammalian cell culture, ideally human immune cell culture.
• Solid understanding of T cell biology and immunology.
• Ability to perform molecular and cell-based assays to improve understanding of engineered Tregs and their impact in preclinical in vitro and in vivo models.
• Assist in the development of novel assays and methods to investigate engineered Treg cell function.
• Aid in the development and testing of novel and relevant immune regulatory assays/models.

We are an exciting, growing biotech company with a culture centered around Innovation, Integrity, Collaboration, Accountability, Respect, and having fun!

Our ambition is to be the leading cell therapy company in the Immune Dysregulation field.