Global Translational Medicine Lead

Global Translational Medicine Lead

About Astellas

At Astellas we are a progressive health partner, delivering value and outcomes where needed.

We pursue innovative science, focussing initially on the areas of greatest potential and then developing solutions where patient need is high, often in rare or under-served disease areas and in life-threatening or life-limiting diseases and conditions.

We work directly with patients, doctors and health care professionals on the front line to ensure patient and clinical needs are guiding our development activities at every stage.

Our global vision for Patient Centricity is to support the development of innovative health solutions through a deep understanding of the patient experience. At Astellas, Patient Centricity isn’t a buzzword - it’s a guiding principle for action. We believe all staff have a role to play in creating a patient-centric culture and integrating an awareness of the patient into our everyday working practices, regardless of our role, team or division.

We work closely with regulatory authorities and payers to find new ways to ensure access to new therapies. We deliver the latest insights and real-world evidence to inform the best decisions for patients and their care-givers, to ensure the medicines we develop continue to provide meaningful outcomes.

Beyond medicines, we support our stakeholder communities to drive initiatives that improve awareness, education, access and ultimately standards of care.

About This Job

As a Global Translational Medicine Lead, your role is to lead the development and execution of the Translational Medicine strategy for developing Astellas. You should have a record of accomplishment in developing and executing translational science/medicine programs with mechanistically grounded biomarker and patient selection strategies. Your ability to work in cross-functional teams is essential to the success of your position.

At Astellas, we recognise that our employees enjoy having a balance between their professional and home lives.  We are proud of our hybrid approach which empowers you to have flexibility on whether to work from home or in the office.

You will be part of an inclusive team that works to develop innovative therapies for patients.

Key Activities for this role:

• Developing and executing translational science and biomarker development plans and defines patient selection strategies for clinical studies.
• Working with clinical team for implementation of biomarker sample collection and bioanalysis.
• Contributing to clinical documents: protocols, study reports, statistical analysis plans, publications, and biomarker sections of regulatory submissions.
• Driving reverse translation, so that clinical results can be used to inform development strategy.
• Thinking strategically and driving innovation. Identifying and leading the evaluation of state -of- the- art technologies for translational and biomarker research.

Essential Knowledge & Experience:

• Extensive professional experience in drug discovery and development in biotech/pharmaceutical company or equivalent translational research experience at an academic institution.
• Breadth of knowledge in cancer biology, cancer genomics, and oncology drug development.
• First-hand experience in the identification and validation of pharmacodynamic and patient selection biomarkers, biomarker assay qualification/qualification and clinical implementation.
• Proven record of leading teams and obtaining high quality and timely results through influencing in a matrix environment.

Educations/Qualifications:

• Advanced science degree (PhD, or Medical Doctor) or equivalent with primary focus in oncology and/or immuno-oncology.

Additional Information:

• Type of role permanent
• Location UK (Addlestone).
• This position follows our hybrid working model. The role requires a blend of home and minimum 1 day per month in our UK office.  Flexibility may be required in line with business needs. Candidates must be located within a commutable distance of the office.

What We Offer:

• A challenging and diversified job in an international setting.
• Opportunity and support for continuous development.
• Inspiring work climate.

We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.